![]() Out of these factors, the β´ is having the function of DNA binding. The transcription factors are sigma factor (initiation), nusA (elongation). The core enzyme component is having five subunits such as β’, β, αI, αII and ω. They are core enzyme and transcription factors. The holoenzyme consists of two main components. This is a complex enzyme which is having a molecular weight of 450 KDa. The RNA polymerase of E coli is extensively studied. The prokaryotic RNA polymerase is a multisubunit heavy enzyme. Summary What is Prokaryotic RNA Polymerase? Side by Side Comparison – Prokaryotic vs Eukaryotic RNA Polymerase in Tabular FormĦ. Similarities Between Prokaryotic and Eukaryotic RNA Polymeraseĥ. On the contrary, the eukaryotic transcription is catalyzed by three different types of RNA polymerases named as RNA polymerase I (transcribe rRNA), RNA polymerase II (transcribe mRNA) and RNA polymerase III (transcribe tRNA). The key difference between Prokaryotic and Eukaryotic RNA Polymerase is that the prokaryotic transcription is performed by a single multi subunit type of RNA polymerase. Prokaryotic and eukaryotic transcription differs mainly due to the difference in RNA polymerase enzyme. RNA polymerase attaches to the promoter region of the gene (DNA) and starts the RNA polymerase-catalyzed transcription. Transcription factors and transcription mediated complexes are guiding the RNA polymerase enzyme to initiate the transcription in a living cell. Generating RNA ( mRNA, rRNA, and tRNA) molecules is an extremely important step in the protein synthesis (translation). During the transcription, RNA polymerase opens the double-stranded DNA so that one DNA strand can be used as a template for the process of synthesizing a mRNA molecule. The official name of RNA polymerase is the DNA-directed RNA polymerase. ![]() RNA polymerase is a high molecular weight enzyme. RNA polymerase is the enzyme which is responsible for the process of transcription that takes place in all living organisms. Key Difference – Prokaryotic vs Eukaryotic RNA Polymerase
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